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HSPD1 antibody

HSPD1 Reactivity: Human, Mouse, Rat, Chicken, Monkey, Dog, Hamster, Cow, Rabbit, Pig, Sheep, Drosophila melanogaster, Xenopus laevis WB, IHC, IF, FACS, ISt, StM Host: Mouse Monoclonal LK1 unconjugated
Catalog No. ABIN6939665
  • Target See all HSPD1 Antibodies
    HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))
    Reactivity
    • 211
    • 123
    • 119
    • 73
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    • 68
    • 63
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    • 60
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    • 46
    • 40
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    • 17
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    • 1
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    • 1
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    • 1
    • 1
    • 1
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    • 1
    • 1
    Human, Mouse, Rat, Chicken, Monkey, Dog, Hamster, Cow, Rabbit, Pig, Sheep, Drosophila melanogaster, Xenopus laevis
    Host
    • 125
    • 114
    • 3
    Mouse
    Clonality
    • 125
    • 115
    Monoclonal
    Conjugate
    • 115
    • 19
    • 10
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    • 2
    • 2
    This HSPD1 antibody is un-conjugated
    Application
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunostaining (ISt), Staining Methods (StM)
    Specificity
    Recognizes a 60 kDa protein, identified as the heat shock protein 60 (hsp60). Its epitope is localized between aa 383-447 of human hsp60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp s), more appropriately called as stress response proteins (srp s). Hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog.
    No Cross-Reactivity
    Bacteria, Nematode, Spinach (Spinacia oleracea)
    Purification
    Purified by Protein A/G
    Immunogen
    Recombinant human HSP60 protein
    Clone
    LK1
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product HSPD1 Primary Antibody
  • Application Notes

    Positive Control: MCF-7 or HeLa or HepG2 cells. Synovial biopsies from patients with juvenile chronic arthritis. Synovial lining layer is strongly positive for hsp60. Breast carcinoma.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Western Blot (0.25-0.5 μg/mL), ,Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))
    Alternative Name
    HSPD1 (HSPD1 Products)
    Synonyms
    CPN60 antibody, GROEL antibody, HLD4 antibody, HSP-60 antibody, HSP60 antibody, HSP65 antibody, HuCHA60 antibody, SPG13 antibody, chaperonin antibody, cpn60 antibody, groel antibody, hld4 antibody, hsp60 antibody, hsp65 antibody, spg13 antibody, 60kDa antibody, Hsp60 antibody, 12 antibody, BP5 antibody, CG12101 antibody, Cpn60 antibody, Dmel\\CG12101 antibody, Dmhsp60 antibody, G62 antibody, HSP60A antibody, Hsp60A antibody, IEF16 antibody, Mmp-P1 antibody, SSP 7506 antibody, d-hsp60 antibody, hsp60A antibody, l(1)10Ac antibody, l(1)BP5 antibody, l(1)G8 antibody, l(1)HM21 antibody, l(1)L12 antibody, l(1)dp025 antibody, cb863 antibody, fa04a05 antibody, fb22d10 antibody, fi27b05 antibody, id:ibd2197 antibody, sb:cb144 antibody, wu:fa04a05 antibody, wu:fb22d10 antibody, wu:fi04a12 antibody, wu:fi27b05 antibody, MIF4 antibody, MNA2 antibody, mopA antibody, groL antibody, crpA antibody, Hspd1-30p antibody, heat shock protein family D (Hsp60) member 1 antibody, heat shock protein family D (Hsp60) member 1 S homeolog antibody, 60 kDa heat shock protein, mitochondrial antibody, heat shock protein 1 (chaperonin) antibody, Heat shock protein 60A antibody, heat shock 60 protein 1 antibody, chaperone ATPase HSP60 antibody, molecular chaperone GroEL antibody, thermosome subunit antibody, chaperonin GroEL antibody, mitochondrial chaperonin antibody, heat shock protein family D member 1 antibody, HSPD1 antibody, hspd1.S antibody, hspd1 antibody, LOC100414401 antibody, Hspd1 antibody, Hsp60A antibody, HSP60 antibody, groEL antibody, MMP_RS07785 antibody, groEl antibody, LOC100136430 antibody
    Molecular Weight
    60kDa
    Gene ID
    3329
    UniProt
    P10809
    Pathways
    Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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