CPB2 antibody

Catalog No. ABIN927029

Product Details anti-CPB2 Antibody

Target: CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This CPB2 antibody is un-conjugated

Application: Please inquire

Purification: Affinity chromatography purified

Immunogen: TAFI antibody was raised in sheep using human TAFI purified from plasma as the immunogen.

Isotype: IgG

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied in liquid form with 10 mM HEPES, pH 7.4, 150 mM NaCl, 50 % (v/v) glycerol.

Handling Advice: Avoid repeated freeze/thaw cycles.
Product will become viscous but will not freeze. Avoid storage in frost-free freezers. Allow product to warm to room temperature and gently mix before use.

Storage: -20 °C

Storage Comment: Store at -10 to -20 °C.

Target Details for CPB2

Target: CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))

Alternative Name: TAFI (CPB2 Products)

Synonyms: CPU antibody, PCPB antibody, TAFI antibody, 1110032P04Rik antibody, 4930405E17Rik antibody, AI255929 antibody, CPR antibody, Cpu antibody, pCPB antibody, zgc:112493 antibody, carboxypeptidase B2 antibody, carboxypeptidase B2 (plasma) antibody, CPB2 antibody, Cpb2 antibody, cpb2 antibody

Background: Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Synonyms: Polyclonal TAFI antibody, Anti-TAFI antibody, Carboxypeptidase B2 antibody, CPB2 antibody, CPU antibody, PCPB antibody.

Pathways: Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis