Cyclin A antibody (C-Term)

Catalog No. ABIN927281

The Rabbit Polyclonal anti-Cyclin A antibody has been validated for WB. It is suitable to detect Cyclin A in samples from Human and Rat.

Quick Overview for Cyclin A antibody (C-Term) (ABIN927281)

Target: Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cyclin A Antibody

Binding Specificity: C-Term

Cross-Reactivity: Rat (Rattus)

Purification: Purified

Immunogen: Ccna2 antibody was raised in rabbit using the C terminal of Ccna2 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

Ccna2 Blocking Peptide, (ABIN5612726), is also available for use as a blocking control in assays to test for specificity of this Ccna2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Cyclin A

Target: Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

Alternative Name: Ccna2

Background: The protein encoded by Ccna2 belongs to the highly conserved cyclin family, whose members are characterized by a  dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases.  Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination  of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all  tissues tested. Synonyms: Polyclonal Ccna2 antibody, Anti-Ccna2 antibody, cyclin A2 antibody, MGC156527 antibody, Ccna2 antibody.

Pathways: PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA