Metabotropic Glutamate Receptor 6 antibody (Middle Region)

Catalog No. ABIN927343

Product Details anti-Metabotropic Glutamate Receptor 6 Antibody

Target: Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Dog, Rabbit, Zebrafish (Danio rerio), Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Metabotropic Glutamate Receptor 6 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Zebrafish (Brachydanio rerio), Rabbit, Dog (Canine), Chicken

Purification: Purified

Immunogen: GRM6 antibody was raised in rabbit using the middle region of GRM6 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

GRM6 Blocking Peptide, catalog no. 33R-2416, is also available for use as a blocking control in assays to test for specificity of this GRM6 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Metabotropic Glutamate Receptor 6

Target: Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))

Alternative Name: GRM6 (GRM6 Products)

Synonyms: mGluR6 antibody, CSNB1B antibody, GPRC1F antibody, MGLUR6 antibody, mGlu6 antibody, GRM6 antibody, BC021919 antibody, Gm3 antibody, Gprc1f antibody, nerg1 antibody, nob2 antibody, nob3 antibody, nob4 antibody, si:dkey-52h10.3 antibody, cb496 antibody, grma antibody, zK13A21.16 antibody, zgc:158329 antibody, glutamate metabotropic receptor 6 antibody, glutamate receptor, metabotropic 6 antibody, glutamate receptor, metabotropic 6a antibody, glutamate receptor, metabotropic 6b antibody, Grm6 antibody, GRM6 antibody, grm6a antibody, grm6b antibody

Background: GRM6 is the receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity.L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. Synonyms: Polyclonal GRM6 antibody, Anti-GRM6 antibody, glutamate receptor, metabotropic 6 antibody, CSNB1B antibody, DKFZp686H1993 antibody, GPRC1F antibody, MGLUR6 antibody, mGlu6 antibody.