DUSP12 antibody (N-Term)

Catalog No. ABIN927409

This Rabbit Polyclonal antibody specifically detects DUSP12 in WB. It exhibits reactivity toward Human, Mouse, Rat and Cow.

Quick Overview for DUSP12 antibody (N-Term) (ABIN927409)

Target: DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))

Reactivity: Human, Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DUSP12 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Cow (Bovine)

Purification: Purified

Immunogen: DUSP12 antibody was raised in rabbit using the N terminal of DUSP12 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

DUSP12 Blocking Peptide, (ABIN5613269), is also available for use as a blocking control in assays to test for specificity of this DUSP12 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for DUSP12

Target: DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))

Alternative Name: DUSP12

Background: DUSP12 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. Synonyms: Polyclonal DUSP12 antibody, Anti-DUSP12 antibody, dual specificity phosphatase 12 antibody, DUSP1 antibody, YVH1 antibody.

Pathways: Regulation of Carbohydrate Metabolic Process