KDM4C antibody (Middle Region)

Catalog No. ABIN927418

This Rabbit Polyclonal antibody specifically detects KDM4C in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for KDM4C antibody (Middle Region) (ABIN927418)

Target: KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM4C antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KDM4C Antibody

Binding Specificity: Middle Region

Cross-Reactivity: Mouse (Murine)

Purification: Purified

Immunogen: JMJD2 C antibody was raised in rabbit using the middle region of JMJD2 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

JMJD2C Blocking Peptide, (ABIN937117), is also available for use as a blocking control in assays to test for specificity of this JMJD2C antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for KDM4C

Target: KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

Alternative Name: JMJD2C

Background: JMJD2C is a member of the Jumonji domain 2 (JMJD2) family. It contains one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Synonyms: Polyclonal JMJD2C antibody, Anti-JMJD2C antibody, jumonji domain containing 2C antibody, FLJ25949 antibody, GASC1 antibody, JHDM3C antibody, KDM4C antibody, KIAA0780 antibody, bA146B14.1 antibody.

Pathways: Nuclear Hormone Receptor Binding, Warburg Effect