KDM4C antibody (C-Term)

Catalog No. ABIN952976

Product Details anti-KDM4C Antibody

Target: KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

Binding Specificity: AA 1030-1056, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM4C antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human JMJD2C / KDM4C (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 1030-1056 amino acids from the C-terminal region of human JMJD2C Genename: KDM4C

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for KDM4C

Target: KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

Alternative Name: JMJD2C / KDM4C (KDM4C Products)

Synonyms: JMJD2C antibody, GASC1 antibody, JHDM3C antibody, TDRD14C antibody, bA146B14.1 antibody, 2410141F18Rik antibody, AA517467 antibody, Gasc1 antibody, Jmjd2c antibody, lysine demethylase 4C antibody, jumonji domain containing 2c antibody, lysine (K)-specific demethylase 4C antibody, KDM4C antibody, Jmjd2c antibody, kdm4c antibody, Kdm4c antibody

Background: This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.Synonyms: GASC-1 protein, GASC1, Gene amplified in squamous cell carcinoma 1 protein, JHDM3C, JmjC domain-containing histone demethylation protein 3C, Jumonji domain-containing protein 2C, KIAA0780, Lysine-specific demethylase 4C

Molecular Weight: 119982 Da

Gene ID: 23081

NCBI Accession: NP_001140166

Pathways: Nuclear Hormone Receptor Binding, Warburg Effect