KDM4C antibody (Middle Region)

Catalog No. ABIN927418

Product Details anti-KDM4C Antibody

Target: KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

Binding Specificity: Middle Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM4C antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine)

Purification: Purified

Immunogen: JMJD2 C antibody was raised in rabbit using the middle region of JMJD2 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

JMJD2C Blocking Peptide, catalog no. 33R-1731, is also available for use as a blocking control in assays to test for specificity of this JMJD2C antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for KDM4C

Target: KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

Alternative Name: JMJD2C (KDM4C Products)

Background: JMJD2C is a member of the Jumonji domain 2 (JMJD2) family. It contains one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Synonyms: Polyclonal JMJD2C antibody, Anti-JMJD2C antibody, jumonji domain containing 2C antibody, FLJ25949 antibody, GASC1 antibody, JHDM3C antibody, KDM4C antibody, KIAA0780 antibody, bA146B14.1 antibody.

Pathways: Nuclear Hormone Receptor Binding, Warburg Effect