SREBF1 antibody (N-Term)

Catalog No. ABIN927656

The Rabbit Polyclonal anti-SREBF1 antibody is suitable to detect SREBF1 in samples from Rat and Mouse. It has been validated for WB.

Quick Overview for SREBF1 antibody (N-Term) (ABIN927656)

Target: SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SREBF1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SREBF1 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Rat (Rattus)

Purification: Purified

Immunogen: SREBF1 antibody was raised in rabbit using the N terminal of SREBF1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

SREBF1 Blocking Peptide, (ABIN937379), is also available for use as a blocking control in assays to test for specificity of this SREBF1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for SREBF1

Target: SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))

Alternative Name: SREBF1

Background: Srebf1 is transcriptional activator that binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Srebf1 also binds to an E-box motif (5'-ATCACGTGA-3'). Srebf1 regulates the transcription of genes for sterol biosynthesis and the LDL receptor gene. Synonyms: Polyclonal SREBF1 antibody, Anti-SREBF1 antibody.

Pathways: AMPK Signaling, Caspase Cascade in Apoptosis, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha