Glutamate Receptor 1 antibody (N-Term)

Catalog No. ABIN927672

This anti-Glutamate Receptor 1 antibody is a Rabbit Polyclonal antibody detecting Glutamate Receptor 1 in WB. Suitable for Human and Mouse.

Quick Overview for Glutamate Receptor 1 antibody (N-Term) (ABIN927672)

Target: Glutamate Receptor 1 (GLUR1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutamate Receptor 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Glutamate Receptor 1 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Mouse (Murine)

Purification: Purified

Immunogen: GRIA1 antibody was raised in rabbit using the N terminal of GRIA1 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

GRIA1 Blocking Peptide, (ABIN937076), is also available for use as a blocking control in assays to test for specificity of this GRIA1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Glutamate Receptor 1

Target: Glutamate Receptor 1 (GLUR1)

Alternative Name: GRIA1

Background: Gria1 is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. Synonyms: Polyclonal Gria1 antibody, Anti-Gria1 antibody, glutamate receptor, ionotropic, AMPA1, alpha 1 antibody, 2900051M01Rik antibody, AI853806 antibody, Glr-1 antibody, Glr1 antibody, GluR-A antibody, GluRA antibody, Glur-1 antibody, Glur1 antibody, HIPA1 antibody.

Pathways: PI3K-Akt Signaling