TGFB1 antibody (Middle Region)

Catalog No. ABIN927687

Product Details anti-TGFB1 Antibody

Target: TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

Binding Specificity: Middle Region

Reactivity: Mouse, Rat, Cow, Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TGFB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Cross-Reactivity: Rat (Rattus), Pig (Porcine), Dog (Canine), Cow (Bovine)

Purification: Purified

Immunogen: TGFB1 antibody was raised in rabbit using the middle region of TGFB1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL or 1:5000 to 1:1000 dilution
Optimal conditions should be determined by the investigator.

Comment:

TGFB1 Blocking Peptide, catalog no. 33R-2202, is also available for use as a blocking control in assays to test for specificity of this TGFB1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for TGFB1

Target: TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

Alternative Name: TGFB1 (TGFB1 Products)

Background: Tgfb1 is a multifunctional protein that control proliferation, differentiation, and other functions in many cell types. Many cells synthesize TGFB1 and essentially all of them have specific receptors for this protein. It regulates the actions of many other growth factors and determines a positive or negative direction of their effects. It plays an important role in bone remodelling. It is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Synonyms: Polyclonal TGFB1 antibody, Anti-TGFB1 antibody.

Pathways: EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints