Fibrillin 1 antibody (N-Term)

Catalog No. ABIN927689

The Rabbit Polyclonal anti-Fibrillin 1 antibody has been validated for WB. It is suitable to detect Fibrillin 1 in samples from Human, Mouse, Rat, Cow, Pig and Dog.

Quick Overview for Fibrillin 1 antibody (N-Term) (ABIN927689)

Target: Fibrillin 1 (FBN1)

Reactivity: Human, Mouse, Rat, Cow, Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibrillin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Fibrillin 1 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Dog (Canine), Mouse (Murine), Rat (Rattus), Cow (Bovine), Pig (Porcine)

Purification: Purified

Immunogen: FBN1 antibody was raised in rabbit using the N terminal of FBN1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

FBN1 Blocking Peptide, (ABIN5613524), is also available for use as a blocking control in assays to test for specificity of this FBN1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Fibrillin 1

Target: Fibrillin 1 (FBN1)

Alternative Name: FBN1

Background: FBN1 is a member of the fibrillin family. FBN1 is a large, extracellular matrix glycoprotein that serve as a structural component of 10-12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome, isolated ectopia lentis, autosomal dominant Weill-Marchesani syndrome, MASS syndrome, and Shprintzen-Goldberg craniosynostosis syndrome. Synonyms: Polyclonal FBN1 antibody, Anti-FBN1 antibody, fibrillin 1 antibody.

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interactome