E2F3 antibody (C-Term)

Catalog No. ABIN927697

This Rabbit Polyclonal antibody specifically detects E2F3 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog and Xenopus laevis.

Quick Overview for E2F3 antibody (C-Term) (ABIN927697)

Target: E2F3

Reactivity: Human, Mouse, Rat, Cow, Dog, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This E2F3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-E2F3 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Frog

Purification: Purified

Immunogen: E2 F3 antibody was raised in rabbit using the C terminal of E2 3 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

E2F3 Blocking Peptide, (ABIN5613286), is also available for use as a blocking control in assays to test for specificity of this E2F3 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for E2F3

Target: E2F3

Background: E2F3 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. Synonyms: Polyclonal E2F3 antibody, Anti-E2F3 antibody, E2F transcription factor 3 antibody.