NUP98 antibody (N-Term)

Catalog No. ABIN927781

This Rabbit Polyclonal antibody specifically detects NUP98 in WB and IF. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Chicken and Xenopus laevis.

Quick Overview for NUP98 antibody (N-Term) (ABIN927781)

Target: NUP98 (Nucleoporin 98kDa (NUP98))

Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Chicken, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP98 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-NUP98 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Frog, Chicken, Zebrafish (Brachydanio rerio)

Purification: Purified

Immunogen: NUP98 antibody was raised in rabbit using the N terminal of NUP98 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL, IF: 2 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

NUP98 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this NUP98 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for NUP98

Target: NUP98 (Nucleoporin 98kDa (NUP98))

Alternative Name: NUP98

Background: The nuclear pore complex (NPC) is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kD nucleoporin is localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kD nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromsome translocatons in acute myelogenous leukemia (AML) and T-cell acute lymphocytic leukemia (T-ALL). Synonyms: Polyclonal NUP98 antibody, Anti-NUP98 antibody, nucleoporin 98kDa antibody, ADIR2 antibody, NUP196 antibody.

Pathways: Stem Cell Maintenance, Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome