HNRNPU antibody (C-Term)

Catalog No. ABIN927938

The Rabbit Polyclonal anti-HNRNPU antibody is suitable to detect HNRNPU in samples from Human. It has been validated for WB.

Quick Overview for HNRNPU antibody (C-Term) (ABIN927938)

Target: HNRNPU (Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPU antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HNRNPU Antibody

Binding Specificity: C-Term

Purification: Purified

Immunogen: HNRNPU antibody was raised in rabbit using the C terminal of HNRNPU as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

HNRNPU Blocking Peptide, (ABIN937875), is also available for use as a blocking control in assays to test for specificity of this HNRNPU antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for HNRNPU

Target: HNRNPU (Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU))

Alternative Name: HNRNPU

Background: HNRNPU belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. HNRNPU contains a RNA binding domain and scaffold-associated region (SAR)-specific bipartite DNA-binding domain. This protein is also thought to be involved in the packaging of hnRNA into large ribonucleoprotein complexes. During apoptosis, this protein is cleaved in a caspase-dependent way. But this cleavage does not affect the function of the encoded protein in RNA metabolism. Synonyms: Polyclonal HNRNPU antibody, Anti-HNRNPU antibody, heterogeneous nuclear ribonucleoprotein U, scaffold attachment factor A antibody, HNRPU antibody, SAF-A antibody, U21.1 antibody.