ESRP2 antibody (C-Term)

Catalog No. ABIN927996

Product Details anti-ESRP2 Antibody

Target: ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ESRP2 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine)

Purification: Purified

Immunogen: Esrp2 antibody was raised in rabbit using the C terminal of Esrp2 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

Esrp2 Blocking Peptide, catalog no. 33R-5174, is also available for use as a blocking control in assays to test for specificity of this Esrp2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for ESRP2

Target: ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

Alternative Name: Esrp2 (ESRP2 Products)

Synonyms: RBM35B antibody, 9530027K23Rik antibody, Rbm35b antibody, RGD1310855 antibody, cb404 antibody, fa07a06 antibody, rbm35b antibody, sb:cb404 antibody, zgc:77254 antibody, epithelial splicing regulatory protein 2 antibody, microRNA 6773 antibody, ESRP2 antibody, Esrp2 antibody, MIR6773 antibody, esrp2 antibody

Background: Esrp2 is an mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. It specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. It also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). It acts by directly binding specific sequences in mRNAs and binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2. Synonyms: Polyclonal Esrp2 antibody, Anti-Esrp2 antibody, epithelial splicing regulatory protein 2 antibody, 9530027K23Rik antibody, Rbm35b antibody.