NUMA1 antibody (C-Term)
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- Target See all NUMA1 Antibodies
- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Chicken, Xenopus laevis
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NUMA1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Rat (Rattus), Mouse (Murine), Chicken, Frog
- Purification
- Purified
- Immunogen
- NUMA1 antibody was raised in rabbit using the C terminal of NUMA1 as the immunogen
- Top Product
- Discover our top product NUMA1 Primary Antibody
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- Application Notes
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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NUMA1 Blocking Peptide, catalog no. 33R-1455, is also available for use as a blocking control in assays to test for specificity of this NUMA1 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
- Alternative Name
- NUMA1 (NUMA1 Products)
- Synonyms
- NUMA antibody, 6720401E04Rik antibody, AA764025 antibody, AL022610 antibody, AU014979 antibody, NUMA1 antibody, NuMA antibody, SP-H antibody, numa antibody, numa1 antibody, nuclear mitotic apparatus protein 1 antibody, nuclear mitotic apparatus protein 1 S homeolog antibody, NUMA1 antibody, Numa1 antibody, numa1 antibody, numa1.S antibody
- Background
- NuMA is a structural element in maintaining nuclear integrity. A critical spindle pole-associated mechanism, called the END (Emi1/NuMA/dynein-dynactin) network, spatially restricts APC/C activity in early mitosis. The entire coding region and exon-intron boundaries of NuMa were screened in 92 familial breast cancer patients. But the results do not support the role of NuMA variants as breast cancer susceptibility alleles. Synonyms: Polyclonal NUMA1 antibody, Anti-NUMA1 antibody, nuclear mitotic apparatus protein 1 antibody, NUMA antibody.
- Pathways
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, M Phase
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