URI1 antibody (Middle Region)

Catalog No. ABIN928444

This Rabbit Polyclonal antibody specifically detects URI1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow and Xenopus laevis.

Quick Overview for URI1 antibody (Middle Region) (ABIN928444)

Target: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Reactivity: Human, Mouse, Rat, Cow, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This URI1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-URI1 Antibody

Binding Specificity: Middle Region

Cross-Reactivity: Rat (Rattus), Mouse (Murine), Cow (Bovine), Frog

Purification: Purified

Immunogen: C19 orf2 antibody was raised in rabbit using the middle region of C19 RF2 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

C19orf2 Blocking Peptide, (ABIN5612439), is also available for use as a blocking control in assays to test for specificity of this C19orf2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for URI1

Target: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Alternative Name: C19orf2

Background: The function of the C19orf2 protein remains unknown.The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Synonyms: Polyclonal C19orf2 antibody, Anti-C19orf2 antibodyFLJ10575 antibody, NNX3 antibody, RMP antibody, URI antibody.