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PYHIN1 antibody (Pyrin and HIN Domain Family, Member 1) (N-Term) Primary Antibody

PYHIN1 Reactivity: Human, Mouse, Rat, Cow, Dog WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN928476
$672.32
Plus shipping costs $45.00
50 μg
local_shipping Shipping to: United States
Delivery in 9 to 11 Business Days
  • Target
    PYHIN1
    Binding Specificity
    • 10
    • 9
    • 7
    • 4
    • 1
    N-Term
    Reactivity
    • 23
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog
    Host
    • 23
    Rabbit
    Clonality
    • 23
    Polyclonal
    Conjugate
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    This PYHIN1 antibody is un-conjugated
    Application
    • 20
    • 18
    • 15
    • 15
    • 2
    Western Blotting (WB)
    Cross-Reactivity
    Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine)
    Purification
    Purified
    Immunogen
    PYHIN1 antibody was raised in rabbit using the N terminal of PYHIN1 as the immunogen
  • Application Notes
    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    PYHIN1 Blocking Peptide, catalog no. 33R-1404, is also available for use as a blocking control in assays to test for specificity of this PYHIN1 antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Concentration
    Lot specific
    Buffer
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • Target
    PYHIN1
    Alternative Name
    PYHIN1 (PYHIN1 Antibody Abstract)
    Synonyms
    IFIX, RP11-520H16.1, 4930422C14, AI447904, Ifi209, Ifix, pyrin and HIN domain family member 1, interferon activated gene 209, PYHIN1, Ifi209
    Background
    PYHIN1 belongs to the HIN-200 family. This protein is major mediator of the tumor suppressor activity of IFN in breast cancer cells. It promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization, and HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells. Synonyms: Polyclonal PYHIN1 antibody, Anti-PYHIN1 antibody, pyrin and HIN domain family, member 1 antibody, IFIX antibody, MGC23885 antibody, RP11-520H16.1 antibody.
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