OAS1 antibody (Middle Region)

Catalog No. ABIN928541

The Rabbit Polyclonal anti-OAS1 antibody is suitable to detect OAS1 in samples from Human, Mouse, Rat, Cow, Dog, Pig and Chicken. It has been validated for WB.

Quick Overview for OAS1 antibody (Middle Region) (ABIN928541)

Target: OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OAS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-OAS1 Antibody

Binding Specificity: Middle Region

Cross-Reactivity: Rat (Rattus), Mouse (Murine), Cow (Bovine), Dog (Canine), Pig (Porcine), Chicken

Purification: Purified

Immunogen: OAS1 antibody was raised in rabbit using the middle region of OAS1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

OAS1 Blocking Peptide, (ABIN5615098), is also available for use as a blocking control in assays to test for specificity of this OAS1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for OAS1

Target: OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))

Alternative Name: OAS1

Background: This protein is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Synonyms: Polyclonal OAS1 antibody, Anti-OAS1 antibody, 2',5'-oligoadenylate synthetase 1, 40/46kDa antibody, IFI-4 antibody, OIAS antibody, OIASI antibody.

Pathways: Hepatitis C