KATNA1 antibody (C-Term)

Catalog No. ABIN928619

Product Details anti-KATNA1 Antibody

Target: KATNA1 (Katanin P60 (ATPase Containing) Subunit A 1 (KATNA1))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KATNA1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine)

Purification: Purified

Immunogen: Katna1 antibody was raised in rabbit using the C terminal of Katna1 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

Katna1 Blocking Peptide, catalog no. 33R-1887, is also available for use as a blocking control in assays to test for specificity of this Katna1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for KATNA1

Target: KATNA1 (Katanin P60 (ATPase Containing) Subunit A 1 (KATNA1))

Alternative Name: Katna1 (KATNA1 Products)

Synonyms: si:dkey-15j16.1 antibody, zgc:110580 antibody, katna1 antibody, katanin catalytic subunit A1 antibody, katanin p60 (ATPase containing) subunit A 1 antibody, katanin p60 (ATPase-containing) subunit A1 antibody, KATNA1 antibody, katna1 antibody, Katna1 antibody

Background: Katna1 severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays, such as that seen during disassembly of interphase microtubules at the G2-M transition.It may also be required for microtubule release from the centrosome after nucleation. In mitotic spindles this could allow depolymerization of the microtubule end proximal to the centrosome, and subsequent poleward microtubule flux. In neurons, microtubule release within the cell body allows their subsequent transport into neuronal processes by microtubule dependent motor proteins. Synonyms: Polyclonal Katna1 antibody, Anti-Katna1 antibody, katanin p60, ATPase-containing subunit A1 antibody.

Pathways: Microtubule Dynamics