OAZ3 antibody (Middle Region)

Catalog No. ABIN928700

Product Details anti-OAZ3 Antibody

Target: OAZ3 (Ornithine Decarboxylase Antizyme 3 (OAZ3))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OAZ3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: OAZ3 antibody was raised in rabbit using the middle region of OAZ3 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

OAZ3 Blocking Peptide, catalog no. 33R-2147, is also available for use as a blocking control in assays to test for specificity of this OAZ3 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for OAZ3

Target: OAZ3 (Ornithine Decarboxylase Antizyme 3 (OAZ3))

Alternative Name: OAZ3 (OAZ3 Products)

Synonyms: Az3 antibody, Oaz-t antibody, AZ3 antibody, OAZ-t antibody, TISP15 antibody, Az-3 antibody, ornithine decarboxylase antizyme 3 antibody, OAZ3 antibody, Oaz3 antibody

Background: Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. In contrast to antizymes 1 and 2, which are widely expressed throughout the body, the expression of this gene product (antizyme 3) is restricted to testis germ cells, and thus it is a possible candidate for heritable forms of human male infertility. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Synonyms: Polyclonal OAZ3 antibody, Anti-OAZ3 antibody, ornithine decarboxylase antizyme 3 antibody, AZ3 antibody, OAZ-t antibody, TISP15 antibody.