LYN antibody (N-Term)

Catalog No. ABIN928741

This Rabbit Polyclonal antibody specifically detects LYN in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for LYN antibody (N-Term) (ABIN928741)

Target: LYN (V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LYN antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LYN Antibody

Binding Specificity: N-Term

Cross-Reactivity: Mouse (Murine)

Purification: Purified

Immunogen: Lyn antibody was raised in rabbit using the N terminal of Lyn as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

Lyn Blocking Peptide, (ABIN5614610), is also available for use as a blocking control in assays to test for specificity of this Lyn antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for LYN

Target: LYN (V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN))

Alternative Name: Lyn

Background: Lyn down regulates expression of stem cell growth factor receptor (KIT). Acts as an effector of EpoR (erythropoietin receptor) in controlling KIT expression and may play a central role in erythroid differentiation during the switch between proliferation and maturation. Synonyms: Polyclonal Lyn antibody, Anti-Lyn antibody, Yamaguchi sarcoma viral, v-yes-1 oncogene homolog antibody, AA407514 antibody, Hck-2 antibody.

Pathways: Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling, Integrin Complex, BCR Signaling