PAIP2 antibody (N-Term)

Catalog No. ABIN928832

Product Details anti-PAIP2 Antibody

Target: PAIP2 (Poly Binding Protein Interacting Protein 2 (PAIP2))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAIP2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: PAIP2 antibody was raised in rabbit using the N terminal of PAIP2 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

PAIP2 Blocking Peptide, catalog no. 33R-6129, is also available for use as a blocking control in assays to test for specificity of this PAIP2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for PAIP2

Target: PAIP2 (Poly Binding Protein Interacting Protein 2 (PAIP2))

Alternative Name: PAIP2 (PAIP2 Products)

Synonyms: PAIP2A antibody, DKFZp469O1314 antibody, 2310050K10Rik antibody, AU045972 antibody, paip2 antibody, poly(A) binding protein interacting protein 2 antibody, polyadenylate-binding protein-interacting protein 2 antibody, poly(A) binding protein interacting protein 2B L homeolog antibody, PAIP2 antibody, Paip2 antibody, paip2b.L antibody

Background: PAIP2 acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. It displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization. Synonyms: Polyclonal PAIP2 antibody, Anti-PAIP2 antibody, polyA binding protein interacting protein 2 antibody, MGC72018 antibody, PAIP2A antibody.