TIM3 antibody (C-Term)

Catalog No. ABIN929144

The Rabbit Polyclonal anti-TIM3 antibody is suitable to detect TIM3 in samples from Human. It has been validated for WB.

Quick Overview for TIM3 antibody (C-Term) (ABIN929144)

Target: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIM3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TIM3 Antibody

Binding Specificity: C-Term

Purification: Purified

Immunogen: HAVCR2 antibody was raised in rabbit using the C terminal of HAVCR2 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

HAVCR2 Blocking Peptide, (ABIN939358), is also available for use as a blocking control in assays to test for specificity of this HAVCR2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for TIM3

Target: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Alternative Name: HAVCR2

Target Type: Virus

Background: HAVCR2 regulates macrophage activation. HAVCR2 inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. HAVCR2 may be also involved in T-cell homing. HAVCR2 is the receptor for LGALS9. Synonyms: Polyclonal HAVCR2 antibody, Anti-HAVCR2 antibody, hepatitis A virus cellular receptor 2 antibody, FLJ14428 antibody, KIM-3 antibody, TIM3 antibody, TIMD3 antibody, Tim-3 antibody.

Pathways: Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints