CERKL antibody (C-Term)

Catalog No. ABIN929363

The Rabbit Polyclonal anti-CERKL antibody has been validated for WB. It is suitable to detect CERKL in samples from Human.

Quick Overview for CERKL antibody (C-Term) (ABIN929363)

Target: CERKL (Ceramide Kinase-Like (CERKL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CERKL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CERKL Antibody

Binding Specificity: C-Term

Purification: Purified

Immunogen: CERKL antibody was raised in rabbit using the C terminal of CERKL as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

CERKL Blocking Peptide, (ABIN936925), is also available for use as a blocking control in assays to test for specificity of this CERKL antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for CERKL

Target: CERKL (Ceramide Kinase-Like (CERKL))

Alternative Name: CERKL

Background: This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts. Synonyms: Polyclonal CERKL antibody, Anti-CERKL antibody, ceramide kinase-like antibody, RP26 antibody.