IGSF8 antibody (Middle Region)

Catalog No. ABIN929376

Product Details anti-IGSF8 Antibody

Target: IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGSF8 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: IGSF8 antibody was raised in rabbit using the middle region of IGSF8 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

IGSF8 Blocking Peptide, catalog no. 33R-4805, is also available for use as a blocking control in assays to test for specificity of this IGSF8 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for IGSF8

Target: IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))

Alternative Name: IGSF8 (IGSF8 Products)

Synonyms: MGC77222 antibody, IGSF8 antibody, MGC151661 antibody, CD316 antibody, CD81P3 antibody, EWI-2 antibody, EWI2 antibody, KCT-4 antibody, LIR-D1 antibody, PGRL antibody, AA033172 antibody, AU041109 antibody, ESTM34 antibody, R75384 antibody, immunoglobulin superfamily, member 8 antibody, immunoglobulin superfamily member 8 antibody, igsf8 antibody, IGSF8 antibody, Igsf8 antibody

Background: IGSF8 may play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. IGSF8 may regulate proliferation and differentiation of keratinocytes. IGSF8 may be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. IGSF8 may also play a role on integrin-dependent morphology and motility functions. IGSF8 may participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain. Synonyms: Polyclonal IGSF8 antibody, Anti-IGSF8 antibody, immunoglobulin superfamily, member 8 antibody, CD316 antibody, CD81P3 antibody, EWI2 antibody, PGRL antibody.