PROX1 antibody (C-Term)
-
- Target See all PROX1 Antibodies
- PROX1 (Prospero Homeobox 1 (PROX1))
-
Binding Specificity
- C-Term
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This PROX1 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- This antibody will detect Prox-1 in the nucleus of lymphatic endothelial cells by immunostaining, and human Prox 1 by western blot.
- Cross-Reactivity
- Human, Mouse (Murine), Rat (Rattus)
- Cross-Reactivity (Details)
- Equal reactivity with Human, Mouse, and Rat
- Purification
- Protein A affinity chromatography
- Immunogen
- Prox 1 antibody was raised in rabbit using recombinant human C-terminal part of Prox-1 (homeo domain and prospero domain) as the immunogen
- Isotype
- IgG
- Top Product
- Discover our top product PROX1 Primary Antibody
-
-
- Application Notes
-
WB: 1-5µg/mL. For other applications, optimal conditions should be determined by end-user
Optimal conditions should be determined by the investigator. - Comment
-
The lyophilized IgG is stable at 4 °C for at least one month and for more than a year when kept at -20 °C. When reconstituted in sterile water to a concentration of >0.5 mg/mL the antibody is stable for at least six weeks at 2-4 °C in the presence of a preservative.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- IgG fraction supplied lyophilizedfrom PBS, pH 7.4 with no preservative.
- Preservative
- Without preservative
- Handling Advice
-
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Storage
- 4 °C/-20 °C
- Storage Comment
- Store lyophilized antibody at -20 °C. Following reconstitution store at 4 °C in the short-term. For longer term storage aliquot and store at -20 °C or -70 °C.
-
-
EphB4 forward signalling regulates lymphatic valve development." in: Nature communications, Vol. 6, pp. 6625, (2016) (PubMed).
: "Lymphatic ontogeny and effect of hypoplasia in developing lung." in: Mechanisms of development, Vol. 128, Issue 1-2, pp. 29-40, (2011) (PubMed).
: "NFATc1 regulates lymphatic endothelial development." in: Mechanisms of development, Vol. 126, Issue 5-6, pp. 350-65, (2009) (PubMed).
: "
-
EphB4 forward signalling regulates lymphatic valve development." in: Nature communications, Vol. 6, pp. 6625, (2016) (PubMed).
-
- Target
- PROX1 (Prospero Homeobox 1 (PROX1))
- Alternative Name
- Prox 1 (PROX1 Products)
- Synonyms
- xprox1 antibody, prospero antibody, PROX1 antibody, LOC100232600 antibody, A230003G05Rik antibody, prox1 antibody, zgc:111888 antibody, prospero homeobox 1 antibody, prospero homeobox 1 L homeolog antibody, prospero homeobox 1a antibody, PROX1 antibody, prox1.L antibody, prox1 antibody, Prox1 antibody, prox1a antibody
- Background
- Prox-1 is a homeobox gene and acts as a master switch for lymphatic endothelial phenotype. Expression of Prox-1 in blood endothelial cells induces expression of other lymphatic marker genes. Together with Podoplanin, Prox-1 can be used to reliably distinguish lympathic vessels from blood vessels. Prox-1 is expressed in CNS, eye, pancreas, liver and heart, and it is one of the most specific and reliable markers for lymphatic endothelial cells. Synonyms: Polyclonal Prox 1 antibody, Anti-Prox 1 antibody, Prox-1 antibody, Prospero related homeobox 1 antibody, Homeobox prospero like protein antibody, Homeobox prospero like protein PROX1 antibody, Prospero homeobox protein 1 antibody, Prospero related homeobox 1 antibody.
- Pathways
- Stem Cell Maintenance, Regulation of Muscle Cell Differentiation
-