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CRSP-2 antibody

CRSP-2 Reactivity: Human DB Host: Mouse Monoclonal 2214C1a unconjugated
Catalog No. ABIN931010
  • Target
    CRSP-2 (Calcitonin Receptor-Stimulating Peptide-2 (CRSP-2))
    Reactivity
    Human
    Host
    Mouse
    Clonality
    Monoclonal
    Application
    Dot Blot (DB)
    Cross-Reactivity
    Human
    Cross-Reactivity (Details)
    Other species not studied.
    Purification
    Protein G affinity chromatography
    Immunogen
    CRSP2 antibody was raised in mouse using recombinant Human Cofactor Required For Sp1 Transcriptional Activation, Subunit 2, 150 Kda (Crsp2)
    Clone
    2214C1a
    Isotype
    IgG1
  • Application Notes
    Optimal conditions should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    Lot specific
    Buffer
    CRSP2 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
  • Target
    CRSP-2 (Calcitonin Receptor-Stimulating Peptide-2 (CRSP-2))
    Alternative Name
    CRSP2
    Synonyms
    CRSP2 antibody, calcitonin receptor-stimulating peptide-2 antibody, CRSP-2 antibody
    Background
    The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation. Synonyms: Monoclonal CRSP2 antibody, Anti-CRSP2 antibody, Cofactor required for Sp1 transcriptional activation subunit 2 antibody, CSRP antibody, RGR1 antibody, EXLM1 antibody, MED14 antibody, CXorf4 antibody, CRSP150 antibody, DRIP150 antibody, TRAP170 antibody, MGC104513 antibody.
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