UBE2K antibody

Catalog No. ABIN931030

This Mouse Monoclonal antibody specifically detects UBE2K in DB. It exhibits reactivity toward Human.

Quick Overview for UBE2K antibody (ABIN931030)

Target: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This UBE2K antibody is un-conjugated

Application: Dot Blot (DB)

Clone: 757C3a

Product Details anti-UBE2K Antibody

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: HIP2 antibody was raised in mouse using recombinant Human Huntingtin Interacting Protein 2 (Hip2)

Isotype: IgG1

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: HIP2 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for UBE2K

Target: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Alternative Name: HIP2

Background: The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis. Synonyms: Monoclonal HIP2 antibody, Anti-HIP2 antibody, HIP2 huntingtin interacting protein 2 antibody, LIG antibody, HYPG antibody, UBE2K antibody.