NRF2 antibody

Catalog No. ABIN931118

The Mouse Monoclonal anti-NRF2 antibody has been validated for ICC and DB. It is suitable to detect NRF2 in samples from Human.

Quick Overview for NRF2 antibody (ABIN931118)

Target: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NRF2 antibody is un-conjugated

Application: Immunocytochemistry (ICC), Dot Blot (DB)

Clone: 437C2a

Product Details anti-NRF2 Antibody

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: NFE2 L2 antibody was raised in mouse using recombinant Human Nuclear Factor (Erythroid-Derived 2)-Like 2

Isotype: IgG1

Application Details

Application Notes: ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: NFE2 L2 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for NRF2

Target: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Alternative Name: NFE2L2

Background: Nuclear factor (erythroid-derived 2)-like 2, also known as NFE2L2 or Nrf2, is a transcription factor that in humans is encoded by the NFE2L2 gene. Nrf2 is a master regulator of the antioxidant response. The antioxidant response is important for the amelioration of oxidative stress. Synonyms: Monoclonal NFE2L2 antibody, Anti-NFE2L2 antibody, Nuclear factor (erythroid -derived 2) like 2 antibody, NRF2 antibody.

Pathways: ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling