UBP1 antibody

Catalog No. ABIN931121

The Mouse Monoclonal anti-UBP1 antibody has been validated for WB, DB and ICC. It is suitable to detect UBP1 in samples from Human.

Quick Overview for UBP1 antibody (ABIN931121)

Target: UBP1 (Upstream Binding Protein 1 (LBP-1a) (UBP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This UBP1 antibody is un-conjugated

Application: Western Blotting (WB), Dot Blot (DB), Immunocytochemistry (ICC)

Clone: 327C1a

Product Details anti-UBP1 Antibody

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: UBP1 antibody was raised in mouse using recombinant Human Upstream Binding Protein 1 (Lbp-1 A)

Isotype: IgG1

Application Details

Application Notes: WB: 0.2-2 µg/mL, ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: UBP1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for UBP1

Target: UBP1 (Upstream Binding Protein 1 (LBP-1a) (UBP1))

Alternative Name: UBP1

Background: UBP1 functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box. Synonyms: Monoclonal UBP1 antibody, Anti-UBP1 antibody, Upstream-binding protein 1 antibody, LBP1A antibody, LBP1B antibody, LBP-1B antibody, LBP-1a antibody, DKFZp686L1745 antibody.