FBXO18 antibody

Catalog No. ABIN931163

The Mouse Monoclonal anti-FBXO18 antibody has been validated for DB and ICC. It is suitable to detect FBXO18 in samples from Human.

Quick Overview for FBXO18 antibody (ABIN931163)

Target: FBXO18 (F-Box Protein, Helicase, 18 (FBXO18))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FBXO18 antibody is un-conjugated

Application: Dot Blot (DB), Immunocytochemistry (ICC)

Clone: 2353C1a

Product Details anti-FBXO18 Antibody

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: FBXO18 antibody was raised in mouse using recombinant Human F-Box Protein, Helicase, 18 (Fbxo18)

Isotype: IgG1

Application Details

Application Notes: ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: FBXO18 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for FBXO18

Target: FBXO18 (F-Box Protein, Helicase, 18 (FBXO18))

Alternative Name: FBXO18

Background: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs, which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different proteinprotein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Synonyms: Monoclonal FBXO18 antibody, Anti-FBXO18 antibody, F-box protein helicase 18 antibody, FBH1 antibody, Fbx18 antibody, FLJ14590 antibody, MGC131916 antibody, MGC141935 antibody, MGC141937 antibody.