FBXO18 antibody (C-Term)

Catalog No. ABIN952282

This Rabbit Polyclonal antibody specifically detects FBXO18 in WB and EIA. It exhibits reactivity toward Human and Mouse.

Quick Overview for FBXO18 antibody (C-Term) (ABIN952282)

Target: FBXO18 (F-Box Protein, Helicase, 18 (FBXO18))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO18 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-FBXO18 Antibody

Binding Specificity: AA 748-777, C-Term

Specificity: This antibody recognizes Mouse FBXO18 (C-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 748-777 amino acids from the C-terminal region of Human FBXO18.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FBXO18

Target: FBXO18 (F-Box Protein, Helicase, 18 (FBXO18))

Alternative Name: FBXO18

Background: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.Synonyms: F-box DNA helicase 1, F-box only protein 18, FBH1, FBX18

Molecular Weight: 117686 Da

Gene ID: 84893

NCBI Accession: NP_116196