MXI1 antibody

Catalog No. ABIN931182

This anti-MXI1 antibody is a Mouse Monoclonal antibody detecting MXI1 in DB. Suitable for Human.

Quick Overview for MXI1 antibody (ABIN931182)

Target: MXI1 (MAX Interactor 1 (MXI1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MXI1 antibody is un-conjugated

Application: Dot Blot (DB)

Clone: MXI1C2a

Product Details anti-MXI1 Antibody

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: MXI1 antibody was raised in mouse using recombinant Human Max Interactor 1

Isotype: IgG1

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: MXI1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for MXI1

Target: MXI1 (MAX Interactor 1 (MXI1))

Alternative Name: MXI1

Background: Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Synonyms: Monoclonal MXI1 antibody, Anti-MXI1 antibody, MAX interacting protein 1 antibody, MAD2 antibody, MXD2 antibody, MXI antibody, MGC43220 antibody.

Pathways: Maintenance of Protein Location