Fibulin 5 antibody

Catalog No. ABIN931297

Product Details anti-Fibulin 5 Antibody

Target: Fibulin 5 (FBLN5)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Fibulin 5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: Fibulin 5 antibody was raised in Mouse using a purified recombinant fragment of Fibulin 5 expressed in E. coli as the immunogen.

Clone: 3F10A5-3F8A12

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Target Details for Fibulin 5

Target: Fibulin 5 (FBLN5)

Alternative Name: Fibulin 5 (FBLN5 Products)

Synonyms: zgc:103575 antibody, FBLN5 antibody, MGC108414 antibody, Fibulin-5 antibody, DKFZp469K0327 antibody, ADCL2 antibody, ARCL1A antibody, ARMD3 antibody, DANCE antibody, EVEC antibody, FIBL-5 antibody, UP50 antibody, A55 antibody, fibulin 5 antibody, fbln5 antibody, FBLN5 antibody, Fbln5 antibody

Background: Fibulin 5 is a recently discovered multifunctional extracellular matrix protein that mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a context-specific manner, and prevents elastinopathy in vivo. Fibulin-5 is abundantly expressed in great vessels and cardiac valves during embryogenesis, and in many adult tissues including the aorta, lung, uterus and skin, all of which contain abundant elastic fibres. Decreased fibulin-5 may contribute to the pathogenesis of aortic dissection by impairing elastic fiber assembly. Fibulin-5 is also a good marker of skin ageing and that the earlier loss of fibulin-5 may involve age-dependent changes in other elastic fibre components. Synonyms: Monoclonal Fibulin 5 antibody, Anti-Fibulin 5 antibody, FBLN5 antibody, FBLN-5 antibody, FBLN 5 antibody.

Pathways: SARS-CoV-2 Protein Interactome