CD80 antibody

Catalog No. ABIN931341

This anti-CD80 antibody is a Mouse Monoclonal antibody detecting CD80 in ELISA and IF. Suitable for Human.

Quick Overview for CD80 antibody (ABIN931341)

Target: CD80

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD80 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Clone: 2A2

Product Details anti-CD80 Antibody

Immunogen: CD80 antibody was raised in Mouse using a purified recombinant fragment of CD80 expressed in E. coli as the immunogen.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10,000, IF: 1:200-1:1000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Target Details for CD80

Target: CD80

Alternative Name: CD80

Background: CD80 is a protein found on activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA-4 (for attenuation of regulation and cellular disassociation). CD80 works in tandem with CD86 to prime T cells. Synonyms: Monoclonal CD80 antibody, Anti-CD80 antibody, B71 antibody, Cluster of Differentiation 80 antibody.

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints