MYL2 antibody

Catalog No. ABIN931412

The Mouse Monoclonal anti-MYL2 antibody is suitable to detect MYL2 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for MYL2 antibody (ABIN931412)

Target: MYL2 (Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MYL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 7C9

Product Details anti-MYL2 Antibody

Immunogen: MYL2 antibody was raised in Mouse using a purified recombinant fragment of MYL2 expressed in E. coli as the immunogen.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10,000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Target Details for MYL2

Target: MYL2 (Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2))

Alternative Name: MYL2

Background: Myosin, light chain 2 (MYL2) encodes the regulatory light chain associated with cardiac myosin beta heavy chain. It is an important protein involved in the regulation of myosin ATPase activity in smooth muscle and Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy. Synonyms: Monoclonal MYL2 antibody, Anti-MYL2 antibody, MLC2 antibody, CMH10 antibody, DKFZp779C0562 antibody, Slow cardiac myosin regulatory light chain 2 antibody, MYL2 antibody, Slow cardiac myosin regulatory light chain 2 Cardiac myosin light chain-2 antibody.

Pathways: Myometrial Relaxation and Contraction