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SKP2 antibody (AA 1-130)
SKP2
Reactivity: Human
WB, ELISA
Host: Mouse
Monoclonal
6G9D10
unconjugated
Product Details anti-SKP2 Antibody
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Target
See all SKP2 Antibodies
SKP2
(S-Phase Kinase-Associated Protein 2 (SKP2))
Binding Specificity
All epitopes for SKP2 antibodies
AA 1-130
Reactivity
All reactivities for SKP2 antibodies
Human
Host
All hosts for SKP2 antibodies
Mouse
Clonality
All clonalities for SKP2 antibodies
Monoclonal
Conjugate
All conjugates for SKP2 antibodies
This SKP2 antibody is un-conjugated
Application
All applications for SKP2 antibodies
Western Blotting (WB), ELISA
Immunogen
SKP2 antibody was raised in Mouse using a purified recombinant fragment of SKP2(aa1-130) expressed in E. coli as the immunogen.
Clone
6G9D10
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
ELISA: 1:10,000, WB: 1:500-1:2000 Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
Lot specific
Buffer
Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term storage. Store at -20 °C for long term storage.
Target Details for SKP2
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Target
SKP2
(S-Phase Kinase-Associated Protein 2 (SKP2))
Alternative Name
SKP2 (SKP2 Products )
Synonyms
FBXL1 antibody, FBL1 antibody, FLB1 antibody, p45 antibody, RGD1562456 antibody, S-phase kinase-associated protein 2 (p45) antibody, S-phase kinase associated protein 2 antibody, Skp2 antibody, SKP2 antibody
Background
SKP2 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs. SKP2 is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, also referred to as p27 or KIP1) predominantly in S phase and interacts with S-phase kinase-associated protein 1 (SKP1 or p19). Synonyms: Monoclonal SKP2 antibody, Anti-SKP2 antibody, SKP-2 antibody, SKP 2 antibody, S phase kinase associated protein 2 antibody, p45 antibody.
Pathways
Mitotic G1-G1/S Phases
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