Survivin antibody

Catalog No. ABIN931440

The Mouse Monoclonal anti-Survivin antibody (Clone 2H5H2) (ABIN931440) specifically detects Survivin in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for Survivin antibody (ABIN931440)

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Survivin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 2H5H2

Product Details anti-Survivin Antibody

Immunogen: Survivin antibody was raised in Mouse using a purified recombinant fragment of Survivin expressed in E. coli as the immunogen.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10,000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Target Details for Survivin

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Alternative Name: Survivin

Background: Survivin is a human gene encoding a structurally unique IAP apoptosis inhibitor. Present during fetal development, survivin is undetectable in terminally differentiated adult tissues. However, survivin becomes prominently expressed in transformed cell lines and in all the most common human cancers of lung, colon, pancreas, prostate and breast, in vivo. Synonyms: Monoclonal Survivin antibody, Anti-Survivin antibody, BIRC5 antibody, Baculoviral Inhibitor of Apoptosis repeat-Containing 5 antibody.

Pathways: Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding