SOX4 antibody

Catalog No. ABIN932199

This anti-SOX4 antibody is a Mouse Monoclonal antibody detecting SOX4 in ICC and DB. Suitable for Human.

Quick Overview for SOX4 antibody (ABIN932199)

Target: SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SOX4 antibody is un-conjugated

Application: Immunocytochemistry (ICC), Dot Blot (DB)

Clone: 154C4a

Product Details anti-SOX4 Antibody

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: SOX4 antibody was raised in mouse using recombinant Human Sry (Sex Determining Region Y)-Box 4 (Sox4)

Isotype: IgG2a

Application Details

Application Notes: ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: SOX4 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for SOX4

Target: SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

Alternative Name: SOX4

Background: This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. Synonyms: Monoclonal SOX4 antibody, Anti-SOX4 antibody, SRY (sex determining region Y) box 4 antibody, EVI16 antibody.