MAX antibody

Catalog No. ABIN932461

Product Details anti-MAX Antibody

Target: MAX (MYC Associated Factor X (MAX))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MAX antibody is un-conjugated

Application: Dot Blot (DB)

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: MAX antibody was raised in mouse using recombinant Human Helix-Loop-Helix Zipper Protein (Max)

Clone: 73C5a

Isotype: IgG2b

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: MAX antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for MAX

Target: MAX (MYC Associated Factor X (MAX))

Alternative Name: MAX (MAX Products)

Synonyms: CG9648 antibody, Dmel\\CG9648 antibody, MAX antibody, bHLHd9 antibody, dMax antibody, dmax antibody, max antibody, bhlhd4 antibody, bhlhd5 antibody, bhlhd6 antibody, bhlhd7 antibody, bhlhd8 antibody, xmax2 antibody, xmax4 antibody, xmax antibody, AA960152 antibody, AI875693 antibody, bHLHd4 antibody, bHLHd5 antibody, bHLHd6 antibody, bHLHd7 antibody, bHLHd8 antibody, fa92b04 antibody, fb52a04 antibody, fb95h11 antibody, wu:fa92b04 antibody, wu:fb52a04 antibody, wu:fb95h11 antibody, zmax antibody, CG9648 gene product from transcript CG9648-RD antibody, MYC associated factor X L homeolog antibody, MYC associated factor X antibody, Max protein antibody, MYC associated factor X S homeolog antibody, myc associated factor X antibody, Max antibody, max.L antibody, MAX antibody, max antibody, max.S antibody

Background: Protein max is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxl1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E-box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature for some of them is unknown. Synonyms: Monoclonal MAX antibody, Anti-MAX antibody, MYC associated factor X antibody.

Pathways: Mitotic G1-G1/S Phases