ADNP antibody

Catalog No. ABIN933134

The Mouse Monoclonal anti-ADNP antibody is suitable to detect ADNP in samples from Human. It has been validated for WB and DB.

Quick Overview for ADNP antibody (ABIN933134)

Target: ADNP (Activity-Dependent Neuroprotector Homeobox (ADNP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADNP antibody is un-conjugated

Application: Western Blotting (WB), Dot Blot (DB)

Clone: 102C1a

Product Details anti-ADNP Antibody

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: ADNP antibody was raised in mouse using recombinant Human Activity-Dependent Neuroprotector Homeobox

Isotype: IgG1

Application Details

Application Notes: WB: 0.2-2 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: ADNP antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for ADNP

Target: ADNP (Activity-Dependent Neuroprotector Homeobox (ADNP))

Alternative Name: ADNP

Background: Vasoactive intestinal peptide (VIP) is a neuroprotective factor that has been shown to have a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. The protein encoded by this gene is upregulated by VIP and may be involved in the stimulatory effect of VIP on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Two transcript variants encoding the same protein have been found for this gene. Synonyms: Monoclonal ADNP antibody, Anti-ADNP antibody, Activity dependent neuroprotector homeobox antibody, ADNP1 antibody.

Pathways: Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process