Leptin antibody
Quick Overview for Leptin antibody (ABIN933792)
Target
See all Leptin (LEP) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Immunogen
- Leptin antibody was raised in mouse using highly pure recombinant human leptin as the immunogen.
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Isotype
- IgG1 kappa
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Application Notes
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ELISA: 2-4 µg/mL, WB: 0.2-0.4 µg/mL
Optimal conditions should be determined by the investigator. -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- Lot specific
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Buffer
- Lyophilized from PBS.
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Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Storage
- 4 °C/-20 °C
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Storage Comment
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- Leptin (LEP)
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Alternative Name
- Leptin
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Background
- Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in various in vivo models. Synonyms: Monoclonal Leptin antibody, Anti-Leptin antibody, Obesity antibody, OB antibody.
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Molecular Weight
- 16.2 kDa (predicted detection band MW)
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Pathways
- JAK-STAT Signaling, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
Target
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