BMP4 antibody

Catalog No. ABIN934071

Cited in 1 publication. The Mouse Monoclonal anti-BMP4 antibody (Clone M912262) (ABIN934071) specifically detects BMP4 in WB, ELISA and InhibAb. The antibody is reactive with Human samples.

Quick Overview for BMP4 antibody (ABIN934071)

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BMP4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Blocking Antibody (InhibAb)

Clone: M912262

Product Details anti-BMP4 Antibody

Purification: Protein A affinity chromatography

Immunogen: BMP4 antibody was raised in mouse using highly pure recombinant human BMP-4 as the immunogen.

Isotype: IgG2b kappa

Application Details

Application Notes: ELISA: 4-8 µg/mL, Inhibition: 0.4-0.6 µg/mL, WB: 0.25-0.5 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

References for anti-BMP4 antibody (ABIN934071)

Calpe, Correia, Sancho-Serra, Krishnadath: "Comparison of newly developed anti-bone morphogenetic protein 4 llama-derived antibodies with commercially available BMP4 inhibitors." in: mAbs, Vol. 8, Issue 4, pp. 678-88, (2017) (PubMed).

Target Details for BMP4

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Alternative Name: BMP4

Background: Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Synonyms: Monoclonal BMP4 antibody, Anti-BMP4 antibody, BMP-4 antibody, Bone Morphogenetic antibody, 4 antibody, BMP-2B antibody, DVR4 antibody.

Molecular Weight: 31-36 kDa (predicted detection band MW)

Pathways: Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development