NGFB antibody
Quick Overview for NGFB antibody (ABIN934073)
Target
See all NGFB AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Purification
- Boric acid precipitation/S-Sepharose. Source: Ascites
-
Immunogen
- beta NGF antibody was raised in mouse using highly pure recombinant human beta-NGF as the immunogen.
-
Isotype
- IgG2b kappa
-
-
-
-
Application Notes
-
ELISA: 2-4 µg/mL, Inhibition: 2.7-4 µg/mL, WB: 4-8 µg/mL
Optimal conditions should be determined by the investigator. -
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Concentration
- Lot specific
-
Buffer
- Lyophilized from PBS.
-
Handling Advice
-
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Storage
- 4 °C/-20 °C
-
Storage Comment
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
-
-
- NGFB (Nerve Growth Factor beta (NGFB))
-
Alternative Name
- beta NGF
-
Background
- Beta-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. beta-NGF is a potent neurotrophic factor that signals through its receptor beta-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. beta-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. Synonyms: Monoclonal beta NGF antibody, Anti-beta NGF antibody, beta-NGF antibody, NGF-beta antibody, Nerve Growth factor antibody.
-
Pathways
- NF-kappaB Signaling, RTK Signaling, Regulation of Cell Size
Target
-