CCL5 antibody

Catalog No. ABIN934074

Cited in 2+ publications. The Mouse Monoclonal anti-CCL5 antibody (Clone M912286) (ABIN934074) specifically detects CCL5 in WB, ELISA and InhibAb. The antibody is reactive with Human samples.

Quick Overview for CCL5 antibody (ABIN934074)

Target: CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CCL5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Blocking Antibody (InhibAb)

Clone: M912286

Product Details anti-CCL5 Antibody

Immunogen: RANTES antibody was raised in mouse using highly pure human RANTES as the immunogen.

Isotype: IgG2b kappa

Application Details

Application Notes: ELISA: 2-4 µg/mL, Inhibition: 3-5 µg/mL, WB: 0.5-1 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

References for anti-CCL5 antibody (ABIN934074)

Zhou, Zhou, Yang, Tian, Feng, Xie, Liu: "Targeted inhibition of the type 2 cannabinoid receptor is a novel approach to reduce renal fibrosis." in: Kidney international, Vol. 94, Issue 4, pp. 756-772, (2019) (PubMed).

Nieto, Zamora, Cantó, Garcia-Planella, Gordillo, Ortiz, Juárez, Vidal: "CSF-1 regulates the function of monocytes in Crohn's disease patients in remission." in: Scientific reports, Vol. 7, Issue 1, pp. 92, (2017) (PubMed).

Target Details for CCL5

Target: CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

Alternative Name: RANTES

Background: RANTES is a protein which has been shown to be a chemoattractant for peripheral blood monocytes. It appears to selectively attract T cells of the CD4+/CD45RO+ phenotype in vitro. Synonyms: Monoclonal RANTES antibody, Anti-RANTES antibody, Regulation upon Activation Normal T cell Express Sequence antibody, CCL5 antibody, SIS-delta antibody.

Molecular Weight: 7.9 kDa (predicted detection band MW)

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration