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- Target See all MME Antibodies
- MME (Membrane Metallo-Endopeptidase (MME))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This MME antibody is un-conjugated
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Application
- Flow Cytometry (FACS)
- Specificity
- The antibody LT10 reacts with an extracellular epitope of CD10 (CALLA - Common acute lymphatic leukemia antigen), a 100 kDa type II integral membrane protein.
- Cross-Reactivity (Details)
- Other not tested, Human
- Purification
- Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).
- Purity
- > 95 % (by SDS-PAGE)
- Immunogen
- mouse NALM-6 leukemia pre-B cell line (tissue/cell preparation)
- Clone
- LT10
- Isotype
- IgG1
- Top Product
- Discover our top product MME Primary Antibody
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anti-Membrane Metallo-Endopeptidase (MME) (AA 52-246) antibody
MME Reactivity: Human WB, IHC, ELISA Host: Mouse Monoclonal 7D4B1 unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 52-352) antibodyMME Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 382-538) antibodyMME Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 501-600) antibodyMME Reactivity: Human, Mouse, Rat FACS, WB, ELISA, ICC, IHC (p), IHC (fro), IF (p), IF (cc) Host: Rabbit Polyclonal unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibodyMME Reactivity: Human WB, IHC, StM Host: Mouse Monoclonal MME-1870 unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 286-428) antibodyMME Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Membrane Metallo-Endopeptidase (MME) antibody (FITC)MME Reactivity: Human FACS Host: Mouse Monoclonal MEM-78 FITC
anti-Membrane Metallo-Endopeptidase (MME) (AA 549-750) antibodyMME Reactivity: Human FACS, WB, ELISA Host: Mouse Monoclonal 6G12E12 unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 549-750) antibodyMME Reactivity: Human FACS, IHC, ELISA Host: Mouse Monoclonal 3G6B11 unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibodyMME Reactivity: Human WB, IHC, ELISA, StM, Coat Host: Mouse Monoclonal MME-1892 unconjugated
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- Application Notes
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Do not freeze.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Do not freeze.
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- Target
- MME (Membrane Metallo-Endopeptidase (MME))
- Alternative Name
- CD10 (MME Products)
- Target Type
- Chemical
- Background
- Membrane metalloendopeptidase,CD10 (neutral endopeptidase –, NEP, common acute lymphocytic leukemia antigen –, CALLA, membrane metallo-endopeptidase –, MME, enkefalinase) is a 100- kDa cell surface zinc metalloprotease, cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptids. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems.,CALLA, Neprilysin, Neutral endopeptidase, Enkephalinase, Atriopeptidase, MME
- Gene ID
- 4311
- UniProt
- P08473
- Pathways
- RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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