CGB antibody (Chorionic Gonadotropin, beta Polypeptide)

Details for Product anti-CGB Antibody No. ABIN94263
Antigen
Reactivity
Human
224
6
5
1
1
1
1
Host
Mouse
128
83
11
3
1
Clonality (Clone)
Monoclonal ()
Conjugate
This CGB antibody is un-conjugated
9
9
7
7
7
7
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), ELISA
119
88
61
30
16
14
10
9
7
7
6
3
2
1
1
1
1
Options
Immunogen Human chorionic gonadotropin.
Clone HCG-61
Isotype IgG2b
Specificity The antibody HCG-61 reacts with beta-subunit of human chorionic gonadotropin, a 40 kDa hormone. hCG belongs to the glycoprotein hormone family together with lutropin (LH), follitropin (FSH) and thyrotropin (TSH). hCG is synthesised by trophoblastic cells of the placenta during pregnancy and stimulates the growth of corpus luteum.
The HCG-61 antibody reacts with association constant 5.1 x 1010 l/mol.
Following cross-reactivity (%) was determined by classic double-antibody RIA using unlabelled hormones: beta-hCG (77), alpha-hCG (1.3), hLH (0.86), hFSH (< 0.5), hTSH (< 0.5).
Cross-Reactivity (Details) Human
Purification Purified by protein-A affinity chromatography
Purity > 95 % (by SDS-PAGE)
Antigen
Alternative Name Chorionic gonadotropin (beta-hCG) (CGB Antibody Abstract)
Background HCG is a protein of the molecular weight about 40 kDa. hCG belongs to the glycoprotein hormone family together with lutropin (LH), follitropin (FSH) and thyrotropin (TSH). hCG is synthesised by trophoblastic cells of the placenta during pregnancy and stimulates the growth of corpus luteum. The other hormones are produced by anterior pituitary gland. All these hormones are structurally related being composed of two noncovalently associated subunits alpha and beta.
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.