Thyroglobulin antibody (TG)

Details for Product anti-TG Antibody No. ABIN94483
Antigen
Reactivity
Human
391
117
116
5
1
1
1
1
1
Host
Mouse
318
69
9
3
1
Clonality (Clone)
Monoclonal ()
Conjugate
This Thyroglobulin antibody is un-conjugated
15
9
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
2
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
144
131
118
113
80
64
24
17
16
13
11
9
6
6
4
2
2
2
2
2
2
2
1
Options
Immunogen thyroid follicular cells
Clone 2H11
Isotype IgG1
Specificity The antibody 2H11 recognizes antigen thyroglobulin (TG), a 610 kDa extracellular secreted glycoprotein specific to the thyroid gland. TG is mainly expressed on thyroid follicular cells (99,1 %).
Cross-Reactivity (Details) Human
Purification Purified by protein-A affinity chromatography
Purity > 95 % (by SDS-PAGE)
Antigen
Alternative Name Thyroglobulin (TG Antibody Abstract)
Background Thyroid disorders are often associated with autoimmune diseases and thyroid cancer.
Pathways Thyroid Hormone Synthesis
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Product cited in: Magro, Perissinotto, Schiappacassi, Goletz, Otto, Müller, Bisceglia, Brown, Ellis, Grasso, Colombatti, Perris: "Proteomic and postproteomic characterization of keratan sulfate-glycanated isoforms of thyroglobulin and transferrin uniquely elaborated by papillary thyroid carcinomas." in: The American journal of pathology, Vol. 163, Issue 1, pp. 183-96, 2003 (PubMed).